Texans vs. Colts predictions, odds, injury news for Saturday’s game

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Houston Texans quarterback C.J. Stroud (7) throws the ball against the Tennessee Titans during the second quarter at NRG Stadium in Houston, Texas., Sunday, Dec. 31, 2023.

It’s a win-and-in contest between two AFC South squads as the Indianapolis Colts host the Houston Texans this Saturday for this Week 18 game. However, it’s not just a playoff spot up for grabs. With the Jacksonville Jaguars set to take on the Tennessee Titans on Sunday, the winner of this game could host a playoff game if the Jaguars lose.

It’s been quite some time since these two teams faced one another, and each team looks drastically different than they did back in Week 2. Anthony Richardson is no longer the quarterback for Indianapolis. Colts running back Jonathan Taylor is healthy, and Texans quarterback C.J. Stroud has vaulted into superstardom. With all that in mind, it’s hard to imagine a similarly one-sided outcome as we saw in Week 2, where the Colts won by double digits.

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